The 17 Best Anti-Inflammatory Supplements Reviews 2019


Acute inflammation is a natural process that helps with healing. But chronic inflammation leads to health problems like arthritis, irritable bowel syndrome, and heart disease. Prevent these outcomes by boosting your body with the best anti-inflammatory supplements.

Low-grade inflammation can negatively impact every system in your body (1). Even if you change your diet to eat fewer inflammatory foods like sugar, you could benefit from supplements. For example, sufficient doses of antioxidants and fatty acids reduce inflammatory markers and improve quality of life for people with chronic conditions (2).

Top Anti-Inflammatory Supplements

We selected the top anti-inflammatory supplements that experts like the Arthritis Foundation recommend (3). Check out the reviews below to find the ones that meet your needs.

Turmeric Curcumin by Vimerson Health

Curcumin comes from the spice turmeric. Its effects on people with arthritis, heart disease, diabetes, cancer, and inflammatory bowel disease have been rigorously studied (4). It also appears to help healthy, active people recover more quickly from muscle soreness caused by exercise.

For better absorption, most supplement manufacturers include black pepper extract also known as BioPerine. That’s what Vimerson Health does with these capsules that include the maximum daily recommended dose of curcumin.

The formula features 95% curcuminoids from 700 mg of turmeric root powder, 300 mg of turmeric root extract along with 10 mg of BioPerine. It’s processed in an FDA-registered facility to be free of gluten, GMO ingredients, and soy.

Tumeric and Ginger by Vimerson Health

Persons with diabetes may find that this combination of turmeric and ginger improves their insulin levels and digestion. But be aware that high doses can thin the blood and cause conflict if you’re already taking aspirin or blood thinners. People who perform vigorous exercise could find that the supplement helps them recover faster and experience less stiffness and pain.

Along with the two main ingredients, Vimerson Heath includes BioPerine to improve absorption. They offer a 100% money-back guarantee if you find that it doesn’t improve the way you feel.

Solgar Wild Alaskan Full Spectrum™ Omega

Solgar’s premium fish oil supplement is rich in omega fatty acids like DHA and EPA. In fact, it blends omega-3, 5, 6, 7, and 9 with Astaxanthin and Vitamin D3 to cover all the bases. The salmon that provide the oil come from cold waters near Alaska. Then, the softgels that encase the oil are free of gluten, sugar, artificial flavors, preservatives, and dyes.

As you may already know, omega fatty acids may have a positive effect on gut health, joints, the heart, and the brain.

Omega-3 Fish & Krill Oil Supplement 500mg  – MegaRed Advanced 4in1

The MegaRed supplement combines fish and krill oil. As a result, it has double the omega-3 than regular fish oil alone. It also absorbs more easily. The company points out that it offers benefits for the eyes, joints, brain, and heart.

Studies reveal that krill oil might lower cholesterol and triglycerides, improve skin elasticity, and reduce PMS symptoms.

NOW Natural Resveratrol 200mg

Resveratrol is an antioxidant derived from fruits with purple skin like blueberries and grapes. It also appears in small amounts and peanuts and red wine. Experiments show that resveratrol could help with ulcerative colitis, insulin resistance, and heart disease (5).

NOW manufactures a variety of supplements including this one with resveratrol in FDA-registered facilities by following GMP (Good Manufacturing Practices). Each dose provides 200 mg, a reasonable balance between the minimum and maximum recommended dosage. They suggest combining it with coenzyme Q10 and Vitamin C.

Garden of Life Heart Resveratrol Supplement

What sets the Garden of Life resveratrol apart from the competition isn’t just ingredients, it’s also the way it’s made. To begin, it comes from organically-grown vegetables and fruits like Cabernet Sauvignon grapes, beets, and kale. Next, it’s fermented to include digestive enzymes and live probiotics. The end result is 350 mg of raw resveratrol per serving. The company uses no fillers or binders either.

Whole Fruit Blueberry Concentrate made from Organic Blueberries by Sports Research

Although Sports Research has developed several powdered supplements, this one comes in softgels. It’s derived from organic blueberries since they contain anthocyanins and flavonoids for a pure polyphenol boost. It’s non-GMO and free of sugar, gluten, and other fillers. Each softgel is made of kosher gelatin and vegetable glycerin. It’s best taken on an empty stomach with water.

Bulletproof Polyphenomenal 2.0

Dave Asprey’s Bulletproof products have skyrocketed in popularity over the past few years. Their Polyphenomenal 2.0 is an upgraded version of the original polyphenol supplement. This essential nutrient is an antioxidant that protects your cells from free radicals.

Free radicals are charged molecules that cause oxidative stress and breakdown cells similar to what you’ll see if you slice an avocado and leave it to sit for a few minutes. If you consume enough polyphenols, you can slow down this process and benefit throughout your body.

The company says that most people consuming Western foods don’t get enough polyphenols from their regular diet even if they drink a lot of coffee. The only downside to the supplement is that you’ll need to take four capsules for a full serving.

Green Tea Extract Supplement with EGCG & Vitamin C by Zenwise Health

With 725 mg of green tea extract in each serving, this supplement from Zenwise Health enhances your metabolism, cognition, and energy. Just as important, it won’t cause jitters. It’s decaffeinated and full of polyphenols. The addition of Vitamin C ensures that you get a variety of antioxidants.

Superior Labs Alpha Lipoic Acid

If you’re in good health, your body makes Alpha Lipoic Acid. But if you’re experiencing chronic inflammation, you might not have enough of this essential fatty acid. It is an antioxidant that’s linked to a healthy metabolism. Studies done on ALA show that it may help with heart disease, cancer, and insulin resistance (6).

Superior Labs creates their ALA supplement in NSF-certified facilities that are audited for quality. It has no synthetic fillers, additives, or heavy metals. Each dose provides 600 mg.

Dr. Danielle Alpha Lipoic Acid, RALA

The difference between this Alpha Lipoic Acid supplement and others on the market is that it has both R-ALA and S-ALA in it. The Alpha R Lipoic Acid is a naturally-occurring form easily absorbed by the body. Moreover, you only need to take one capsule per day to get 550 mg in total.

Integrative Therapeutics – Berberine Complex

You may not have heard of Berberine if you’re new to anti-inflammatory supplements. But if you are dealing with irritable bowel syndrome or ulcerative colitis, this is one to investigate. Berberine appears to reduce diarrhea and intestinal inflammation by balancing healthy bacteria in the digestive tract. It’s also similar to antidiabetic drugs like Metformin (7).

Integrative Therapeutics obtains Berberine from plants like Oregon grapes, goldenseal, and barberry. Each serving of two veggie capsules is free of gluten, soy, dairy, artificial flavors, preservatives, and dyes.

Thorne Research – Berberine-500

Thorne Research also makes Berberine. As they point out, they’ve been in the business for more than three decades. They manufacture in the United States in a facility that’s certified for quality and purity by a third-party.

Each capsule has 500 mg of Berberine HCl. They are free of GMOs, preservatives, soy, gluten, nuts, and other allergens.

Now Foods Organic Spirulina Tablets

Do you remember when juices with spirulina went from something “health nuts” made at home in their blenders to going mainstream at juice bars? Now you don’t need to harvest fresh spirulina algae to reap the benefits. Instead, you can simply take these flavor-free tablets. Each one has 500 mg, so if you take six, you get the recommended daily dose of 3000 mg.

What makes spirulina special is that it stops the enzyme called NOX (NADPH oxidase) which has an unfortunate tendency to attack organs. When it works in its normal capacity to defend your body, it kills infections. But when it gets out of control, it leads problems like fatigue and allergic rhinitis.

NOW’s supplement is created from 100% natural Hawaiian spirulina. It’s manufactured and packaged in the USA and Canada.

Pure Hawaiian Spirulina Powder by NUTREX HAWAII

The NUTREX powder is also made from pure Hawaiian spirulina grown on the Big Island. The vegan formula is made in a GMP-certified facility. It’s free of gluten and soy and has no fillers, dyes, or preservatives. Take 1 teaspoon daily with meals or in between.

Nature’s Way Boswellia

Boswellia is better known as frankincense. It’s a popular remedy in both Asian and African medicine. It’s useful for treating asthma, arthritis, inflammatory bowel disease, and possibly even cancer. It has an additional benefit beyond reducing inflammation caused by leukotrienes because it also diminishes pain (8).

Nature’s Way uses standardized 65% Boswellic acids from tree resin. Each serving has 307 mg.

Solaray Boswellia Resin Extract 450 mg

Solaray’s Boswellia supplement contains an additional ingredient called Harpagofito. This is also known as Devil’s Claw, a traditional South African remedy for arthritis (9). As of the early 2000s, there were more than a dozen clinical trials studying its effectiveness. It may be safer than taking non-steroidal anti-inflammatory medications.


We hope this article inspired you today. The good news is that modern medicine is actively studying many of these anti-inflammatory supplements. One day they may take the place of medications that have undesirable side effects. In the meantime, you can enjoy the benefits without a prescription. Our team is always on the lookout for the best nature has to offer. So be sure to let us know what you tried and how it worked for you.